Plasma Clearance of Iohexol in Hemodialysis Patients Requires Prolonged Blood Sampling Publication date: May 2016 Source:American Journal of Kidney Diseases, Volume 67, Issue 5 Author(s): Gunnar Sterner, Karl-Göran Prütz
Iohexol clearance has been shown to be a marker of the glomerular filtration rate in patients with normal and impaired renal function. Investigators from Minneapolis used the iohexol clearance to estimate RRF in hemodialysis patients and compared iohexol clearance to urea clearance.
Residual renal function (RRF) may contribute significantly to the total dialysis prescription. Conventional quantitation of RRF in hemodialysis (HD) patients is measured by urea clearance and requires a 24-hour urine collection which is often difficult to perform and inaccurate. The renal clearance of Use of iohexol to quantify hemodialysis delivered and residual renal function. This result agrees with data from anuric patients for whom extrarenal iohexol clearance was measured between 2 hemodialysis sessions.
På remissen ska anges om beställningen avser enbart iohexolkoncentration eller beräkning av iohexol-clearance (GFR). Analys av iohexol och beräkning av iohexol-clearance (GFR) utförs av Klinisk kemi SU/Sahlgrenska. Use of iohexol to quantify hemodialysis delivered and residual renal function. Background. Classically, urea (molecular wt 5 60) is used to determine the urea reduction ratio (URR) or clearance, based on volume of distribution (Kt/V). These methods are subject to many errors.
With Special Reference to Peritoneal Transport Rates and Solute Clearance. Jose A. Diaz- Buxo, MD, METHODS: We assessed a new technique of measuring iohexol clearance using timed dried capillary blood spots. A reference GFR was measured in 81 21 Feb 2020 Dialysis immediately after contrast administration has been vascular access, as the clearance with peritoneal dialysis would be far too slow to Plasma concentrations of iohexol can be used for measurement of GFR iohexol determinations (urinary clearance; HEXU / Iohexol, Timed Collection, Urine).
Associates of Mortality Among Peritoneal Dialysis Patients. With Special Reference to Peritoneal Transport Rates and Solute Clearance. Jose A. Diaz- Buxo, MD,
Calculated urea clearance (C(urea)), 247+/-21 ml/min, significantly overestimated DDQ C(urea) (157+/-10 ml/min P < 0.001). Total body clearance of iohexol (C mg iodine/ml) was administered to 42 hemodialysis patients following routine HD. A single blood sample was obtained approximately 44 hours later (pre-HD) to determine the plasma clearance of iohexol using x-ray fluorescence methods. The use of iohexol clearance to determine GFR in patients with severe chronic renal failure–A comparison between different clearance techniques. Clin Nephrol.
extrarenal iohexol clearance was measured between 2 hemodial-ysis sessions.3,4 Thus, we believe that properly performed plasma iohexol clearance using long sampling time is a suitable technique for estimating residual kidney function in patients receiving hemodi-alysis. The established method based on urine collection and blood
Hemodialysis Patients without Urine Collection', Seminars in with KRU in haemodialysis patients to see if iohexol clearance can be used to substitute KRU. Residual renal function (RRF) may contribute significantly to the total dialysis prescription. Conventional quantitation of RRF in hemodialysis (HD) patients is 13 Feb 2017 To remove residual unbound FITC, the solution was dialyzed in 1.8 L of 0.85% sodium chloride at room temperature for 24 h using 1 kDa dialysis 30 Sep 2019 Precision of plasma clearance of iohexol for estimation of GFR in NKF, Retrophin, Omeros, Reata Pharmaceuticals and Dialysis Clinic, Inc. 9 Apr 2018 Neither hemodialysis nor peritoneal dialysis can normalize POx levels in CKD patients; GFR MEASUREMENT BY IOHEXOL CLEARANCE. 9 Sep 2016 1Department of Nephrology, Dialysis and Transplantation, University of Liège Iohexol plasma clearance represents the best chance for 20 Jun 2009 patients with end-stage renal disease, dialysis techniques patients and patients on hemodialysis [33, 34, 42]. such as iohexol clearance. Associates of Mortality Among Peritoneal Dialysis Patients.
The use of iohexol clearance to determine GFR in patients with severe chronic renal failure--a comparison between different clearance techniques. The blood clearance of iosimenol during clinical hemodialysis was predicted as, on average, approximately 85 mL/min with the high-flux membranes and 47 mL/min with the low-flux membrane. 1998-09-01 · Determination of residual renal function with iohexol clearance in hemodialysis patients Kidney Int , 49 ( 1996 ) , pp. 232 - 235 Article Download PDF CrossRef View Record in Scopus Google Scholar
title = "Plasma clearance of iohexol in hemodialysis patients requires prolonged blood sampling",
Determination of residual renal function with iohexol clearance in hemodialysis patients.
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The blood clearance of iosimenol during clinical hemodialysis was predicted as, on average, approximately 85 mL/min with the high-flux membranes and 47 mL/min with the low-flux membrane. 1998-09-01 · Determination of residual renal function with iohexol clearance in hemodialysis patients Kidney Int , 49 ( 1996 ) , pp. 232 - 235 Article Download PDF CrossRef View Record in Scopus Google Scholar
title = "Plasma clearance of iohexol in hemodialysis patients requires prolonged blood sampling",
Determination of residual renal function with iohexol clearance in hemodialysis patients. Residual renal function (RRF) may contribute significantly to the total dialysis prescription.
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Repeated single sample iohexol clearances gave a coefficient of variation of 15%. During dialysis the clearances of iohexol and iodixanol were, respectively, 69 ± 16 and 58 ± 11 ml/min/1.73 m2 when calculated from a single-pool model (hemodialysis clearance of CM from plasma).
1998-09-01 · Determination of residual renal function with iohexol clearance in hemodialysis patients Kidney Int , 49 ( 1996 ) , pp. 232 - 235 Article Download PDF CrossRef View Record in Scopus Google Scholar title = "Plasma clearance of iohexol in hemodialysis patients requires prolonged blood sampling", Determination of residual renal function with iohexol clearance in hemodialysis patients. Residual renal function (RRF) may contribute significantly to the total dialysis prescription. Conventional quantitation of RRF in hemodialysis (HD) patients is measured by urea clearance and requires a 24-hour urine collection which is often difficult to perform and inaccurate.
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In the Original Investigation article entitled “Comparability of Plasma Iohexol Clearance Across Population-Based Cohorts” that appeared in the July 2020 issue of AJKD (Eriksen et al, volume 76, issue 1, pages 54-62), the name of one of the authors was spelled incorrectly. The name Olafur S. Indridasson should have appeared as Olafur S. Indridason. The author list has been corrected in the
The renal clearance of iohexol was evaluated as an alternative method for RRF assessment (iohexol-derived RRF) in hemodialysis patients. An intravenous bolus of iohexol (12 ml; 300 mg iodine/ml) was administered to 42 hemodialysis patients following routine HD. Thus, we believe that properly performed plasma iohexol clearance using long sampling time is a suitable technique for estimating residual kidney function in patients receiving hemodialysis. The established method based on urine collection and blood sampling is less suited for everyday clinical practice. between plasma clearance and renal clearance of iohexol.3 For dialysis-dependent patients with chronic kidney failure, the time at which the last blood sample is drawn should be delayed even further.